The implication of electrocatalysis in MCR strategy:: Electrocatalytic multicomponent transformation of cyclic 1,3-diketones, aldehydes and malononitrile into substituted 5,6,7,8-tetrahydro-4H-chromenes

被引：52

作者：

Elinson, Michail N. ^{[1
]}

Dorofeev, Alexander S. ^{[1
]}

Feducovich, Sergey K. ^{[1
]}

Gorbunov, Sergey V. ^{[1
]}

Nasybullin, Ruslan F. ^{[1
]}

Miloserdov, Fedor M. ^{[1
]}

Nikishin, Gennady I. ^{[1
]}

机构：

[1] ND Zelinskii Inst Organ Chem, Leninsky Prospekt 47, Moscow 119991, Russia

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 2006卷 / 19期

关键词：

oxygen heterocycles; electrochemistry; homogeneous catalysis; multicomponent reactions; cyclization;

D O I：

10.1002/ejoc.200600544

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The electrochemically induced catalytic multicomponent transformation of cyclic 1,3-diketones, aldehydes and malononitrile in alcoholic solvents results in the formation of substituted 5,6,7,8-tetrahydro-4H-chromenes in 85-95% yields. The reaction is performed in an undivided cell in the presence of sodium bromide as an electrolyte. The application of this efficient electrocatalytic method to the formation of tetrahydro-4H-chromenes is beneficial for diversity-oriented large-scale processes. The novel concept of an electrocatalytic multicomponent reaction is also ecologically sound. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006).

引用

页码：4335 / 4339

页数：5

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