blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513

被引：87

作者：

Arduino, SM

Roy, PH

Jacoby, GA

Orman, BE

Pineiro, SA

Centron, D

机构：

[1] Univ Buenos Aires, Fac Med, Dept Microbiol, RA-1121 Buenos Aires, DF, Argentina

[2] Univ Laval, Fac Sci & Genie, Dept Biochim, Ste Foy, PQ G1K 7P4, Canada

[3] CHU Laval, Ctr Rech, Ctr Rech Infectiol, Quebec City, PQ G1V 4G2, Canada

[4] Lahey Clin Fdn, Burlington, MA USA

[5] Edith Nourse Rogers Mem Vet Adm Hosp, Bedford, MA 01730 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 07期

关键词：

D O I：

10.1128/AAC.46.7.2303-2306.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Examination of the bla(CTX-M-2) gene in plasmid pMAR-12 by sequencing and PCR analysis revealed that the bla gene and the surrounding DNA, which is closely related (99% homology) to the Kluyvera ascorbata chromosomal DNA that contains the bla(KLUA-1) gene, are located in a complex sul1-type integron, termed 105, that includes Orf513. It is possible that blaCTX-M-2 was acquired by plasmid pMAR-12 through an uncharacterized recombinational event in which Orf513 could be involved.

引用

页码：2303 / 2306

页数：4

共 21 条

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