Whole-body fluorine-18 fluordeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in staging of advanced uveal melanoma

被引:26
作者
Freudenberg, LS
Schueler, AO
Beyer, T
Antoch, G
Kühl, H
Bornfeld, N
Bockisch, A
Egelhof, T
机构
[1] Univ Hosp, Dept Nucl Med, Essen, Germany
[2] Univ Hosp, Dept Ophthalmol, Essen, Germany
[3] Univ Hosp, Dept Radiol, Essen, Germany
关键词
dual-modality; fluordeoxyglucose (FDG); positron emission tomography (PET); positron emission tomography/computed tomography (PET/CT); staging; uveal melanoma;
D O I
10.1016/j.survophthal.2004.06.008
中图分类号
R77 [眼科学];
学科分类号
100212 [眼科学];
摘要
Fluorine-18 fluordeoxyglucose positron emission tomography (FDG-PET) is an useful tool in diagnosing and monitoring of malignant cutaneous melanoma. However, the feasibility and usefulness of FDG-PET in uveal melanoma is not yet established. We present a patient with suspected advanced uveal melanoma who underwent combined FDG-PET/computed tomography (CT) for staging. FDG-PET/CT images demonstrated vital intraocular tumor. Anatomical assignment of the malignancy to the choroid was possible by means of the coregistered computed tomography. Furthermore, PET revealed an unknown otherwise undetected vital liver metastasis. We conclude that combined FDG-PET/CT has potential to further improve staging and therapy planning in patients with advanced uveal melanoma.
引用
收藏
页码:537 / 540
页数:4
相关论文
共 17 条
[1]
Beyer T, 2000, J NUCL MED, V41, P1369
[2]
CUTLER SJ, 1975, 3 NATL CANC SURVEY I
[3]
A REVIEW OF MORTALITY FROM CHOROIDAL MELANOMA .2. A METAANALYSIS OF 5-YEAR MORTALITY-RATES FOLLOWING ENUCLEATION, 1966 THROUGH 1988 [J].
DIENERWEST, M ;
HAWKINS, BS ;
MARKOWITZ, JA ;
SCHACHAT, AP .
ARCHIVES OF OPHTHALMOLOGY, 1992, 110 (02) :245-250
[4]
[5]
Effectiveness of positron emission tomography for the detection of melanoma metastases [J].
Holder, WD ;
White, RL ;
Zuger, JH ;
Easton, EJ ;
Greene, FL .
ANNALS OF SURGERY, 1998, 227 (05) :764-771
[6]
Attenuation correction for a combined 3D PET/CT scanner [J].
Kinahan, PE ;
Townsend, DW ;
Beyer, T ;
Sashin, D .
MEDICAL PHYSICS, 1998, 25 (10) :2046-2053
[7]
MRI, ANTIBODY-GUIDED SCINTIGRAPHY, AND GLUCOSE-METABOLISM IN UVEAL MELANOMA [J].
LUCIGNANI, G ;
PAGANELLI, G ;
MODORATI, G ;
PIERALLI, S ;
RIZZO, G ;
MAGNANI, P ;
COLOMBO, F ;
ZITO, F ;
LANDONI, C ;
SCOTTI, G ;
BRANCATO, R ;
FAZIO, F .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1992, 16 (01) :77-83
[8]
Mijnhout GS, 2001, CANCER-AM CANCER SOC, V91, P1530, DOI 10.1002/1097-0142(20010415)91:8<1530::AID-CNCR1162>3.3.CO
[9]
2-R
[10]
Glucose metabolism and pathological findings in uveal melanoma: Preliminary results [J].
Modorati, G ;
Lucignani, G ;
Landoni, C ;
Freschi, M ;
Trabucchi, G ;
Fazio, F ;
Brancato, R .
NUCLEAR MEDICINE COMMUNICATIONS, 1996, 17 (12) :1052-1056