Attenuation correction for a combined 3D PET/CT scanner

被引:668
作者
Kinahan, PE [1 ]
Townsend, DW [1 ]
Beyer, T [1 ]
Sashin, D [1 ]
机构
[1] Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15213 USA
关键词
dual modality; PET and CT; attenuation correction;
D O I
10.1118/1.598392
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
In this work we demonstrate the proof of principle of CT-based attenuation correction of 3D positron emission tomography (PET) data by using scans of bone and soft tissue equivalent phantoms and scans of humans. This method of attenuation correction is intended for use in a single scanner that combines volume-imaging (3D) PET with x-ray computed tomography (CT) for the purpose of providing accurately registered anatomical localization of structures seen in the PET image. The goal of this work is to determine if we can perform attenuation correction of the PET emission data using accurately aligned CT attenuation information. We discuss possible methods of calculating the PET attenuation map at 511 keV based on CT transmission information acquired from 40 keV through 140 keV. Data were acquired on separate CT and PET scanners and were aligned using standard image registration procedures. Results are presented on three of the attenuation calculation methods: segmentation, scaling, and our proposed hybrid segmentation/scaling method. The results are compared with those using the standard 3D PET attenuation correction method as a gold standard. We demonstrate the efficacy of our proposed hybrid method for converting the CT attenuation map from an effective CT photon energy of 70 keV to the PET photon energy of 511 keV. We conclude that using CT information is a feasible way to obtain attenuation correction factors for 3D PET. (C) 1998 American Association of Physicists in Medicine. [S0094-2405(98)01710-6].
引用
收藏
页码:2046 / 2053
页数:8
相关论文
共 21 条
  • [1] ENERGY-SELECTIVE RECONSTRUCTIONS IN X-RAY COMPUTERIZED TOMOGRAPHY
    ALVAREZ, RE
    MACOVSKI, A
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 1976, 21 (05) : 733 - 744
  • [2] [Anonymous], 1969, 29 NSRDSNBS
  • [3] A CONVOLUTION-SUBTRACTION SCATTER CORRECTION METHOD FOR 3D PET
    BAILEY, DL
    MEIKLE, SR
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 1994, 39 (03) : 411 - 424
  • [4] ECAT ART - A continuously rotating PET camera: Performance characteristics, initial clinical studies, and installation considerations in a nuclear medicine department
    Bailey, DL
    Young, H
    Bloomfield, PM
    Meikle, SR
    Glass, D
    Myers, MJ
    Spinks, TJ
    Watson, CC
    Luk, P
    Peters, AM
    Jones, T
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1997, 24 (01) : 6 - 15
  • [5] Beyer T, 1994, IEEE NUCL SCI S MED
  • [6] Attenuation correction of SPECT using X-ray CT on an emission-transmission CT system: Myocardial perfusion assessment
    Blankespoor, SC
    Wu, X
    Kalki, K
    Brown, JK
    Tang, HR
    Cann, CE
    Hasegawa, BH
    [J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1996, 43 (04) : 2263 - 2274
  • [7] ATTENUATION CORRECTION IN PET USING SINGLE-PHOTON TRANSMISSION MEASUREMENT
    DEKEMP, RA
    NAHMIAS, C
    [J]. MEDICAL PHYSICS, 1994, 21 (06) : 771 - 778
  • [8] GROOTOONK S, 1992, IEEE NUCL SCI S MED
  • [9] A PROTON PROFILE MONITOR USING AN AMORPHOUS-SILICON PHOTODIODE-ARRAY
    HASEGAWA, K
    SUGIURA, H
    MOCHIKI, K
    TAKAHASHI, H
    HAYAKAWA, Y
    INADA, T
    [J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1993, 40 (04) : 569 - 572
  • [10] *INT COMM RAD UN M, 1989, 44 INT COMM RAD UN M