Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

被引:1363
作者
Zhou, Hongyan [1 ]
Wu, Shili [5 ]
Joo, Jin Young [6 ]
Zhu, Saiyong [1 ]
Han, Dong Wook [6 ]
Lin, Tongxiang [1 ]
Trauger, Sunia [2 ,3 ]
Bien, Geoffery [5 ]
Yao, Susan [5 ]
Zhu, Yong [5 ]
Siuzdak, Gary [2 ,3 ]
Schoeler, Hans R. [6 ]
Duan, Lingxun [4 ]
Ding, Sheng [1 ]
机构
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA
[3] Scripps Res Inst, Ctr Mass Spectrometry, La Jolla, CA 92037 USA
[4] LD Biopharma Inc, San Diego, CA 92130 USA
[5] ProteomTech Inc, Costa Mesa, CA 92626 USA
[6] Max Planck Inst Mol Biomed, Dept Cell & Dev Biol, D-48149 Munster, Germany
关键词
HUMAN FIBROBLASTS; INDUCTION; P53; OCT4;
D O I
10.1016/j.stem.2009.04.005
中图分类号
Q813 [细胞工程];
学科分类号
摘要
引用
收藏
页码:381 / 384
页数:4
相关论文
共 21 条
[1]   Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes [J].
Aasen, Trond ;
Raya, Angel ;
Barrero, Maria J. ;
Garreta, Elena ;
Consiglio, Antonella ;
Gonzalez, Federico ;
Vassena, Rita ;
Bilic, Josipa ;
Pekarik, Vladimir ;
Tiscornia, Gustavo ;
Edel, Michael ;
Boue, Stephanie ;
Izpisua Belmonte, Juan Carlos .
NATURE BIOTECHNOLOGY, 2008, 26 (11) :1276-1284
[2]   Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 [J].
Danwei Huangfu ;
Osafune, Kenji ;
Maehr, Rene ;
Guo, Wenjun ;
Eijkelenboom, Astrid ;
Chen, Shuibing ;
Muhlestein, Whitney ;
Melton, Douglas A. .
NATURE BIOTECHNOLOGY, 2008, 26 (11) :1269-1275
[3]   Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds [J].
Huangfu, Danwei ;
Maehr, Rene ;
Guo, Wenjun ;
Eijkelenboom, Astrid ;
Snitow, Melinda ;
Chen, Alice E. ;
Melton, Douglas A. .
NATURE BIOTECHNOLOGY, 2008, 26 (07) :795-797
[4]   p53 protein transduction therapy: Successful targeting and inhibition of the growth of the bladder cancer cells [J].
Inoue, M ;
Tomizawa, K ;
Matsushita, M ;
Lu, YF ;
Yokoyama, T ;
Yanai, H ;
Takashima, A ;
Kumon, H ;
Matsui, H .
EUROPEAN UROLOGY, 2006, 49 (01) :161-168
[5]   Virus-free induction of pluripotency and subsequent excision of reprogramming factors [J].
Kaji, Keisuke ;
Norrby, Katherine ;
Paca, Agnieszka ;
Mileikovsky, Maria ;
Mohseni, Paria ;
Woltjen, Knut .
NATURE, 2009, 458 (7239) :771-U112
[6]   Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors [J].
Kim, Jeong Beom ;
Zaehres, Holm ;
Wu, Guangming ;
Gentile, Luca ;
Ko, Kinarm ;
Sebastiano, Vittorio ;
Arauzo-Bravo, Marcos J. ;
Ruau, David ;
Han, Dong Wook ;
Zenke, Martin ;
Schoeler, Hans R. .
NATURE, 2008, 454 (7204) :646-U54
[7]   Recombinant, refolded tetrameric p53 and gonadotropin-releasing hormone-p53 slow proliferation and induce apoptosis in p53-deficient cancer cells [J].
LaFevre-Bernt, Michelle ;
Wu, Shili ;
Lin, Xinli .
MOLECULAR CANCER THERAPEUTICS, 2008, 7 (06) :1420-1429
[8]   Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors [J].
Li, Wenlin ;
Wei, Wei ;
Zhu, Saiyong ;
Zhu, Jinliang ;
Shi, Yan ;
Lin, Tongxiang ;
Hao, Ergeng ;
Hayek, Alberto ;
Deng, Hongkui ;
Ding, Sheng .
CELL STEM CELL, 2009, 4 (01) :16-19
[9]   The NH2 terminus of influenza virus hemagglutinin-2 subunit peptides enhances the antitumor potency of polyarginine-mediated p53 protein transduction [J].
Michiue, H ;
Tomizawa, K ;
Wei, FY ;
Matsushita, M ;
Lu, YF ;
Ichikawa, T ;
Tamiya, T ;
Date, I ;
Matsui, H .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (09) :8285-8289
[10]   Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors [J].
Okita, Keisuke ;
Nakagawa, Masato ;
Hong, Hyenjong ;
Ichisaka, Tomoko ;
Yamanaka, Shinya .
SCIENCE, 2008, 322 (5903) :949-953