Reversible and chemically programmable micelle assembly with DNA block-copolymer amphiphiles

被引：172

作者：

Li, Z

Zhang, Y

Fullhart, P

Mirkin, CA

机构：

[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA

[2] Northwestern Univ, Inst Nanotechnol, Evanston, IL 60208 USA

来源：

NANO LETTERS | 2004年 / 4卷 / 06期

关键词：

D O I：

10.1021/nl049628o

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a general solid-phase synthesis strategy for a novel class of DNA block copolymer amphiphiles. The assembled spherical micelle structures exhibit recognition properties defined by their DNA sequences and can be used to build higher-ordered structures through hybridization with materials that possess complementary DNA. This work is an important step toward creating DNA modified structures that can act as phase transfer agents and carriers of nanovesicles.

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收藏

页码：1055 / 1058

页数：4

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