Real-time measurement of in-vitro and in-vivo blood flow with Fourier domain optical coherence tomography

被引：2

作者：

Leitgeb, R ^{[1
]}

Schmetterer, L ^{[1
]}

Drexler, W ^{[1
]}

Berisha, F ^{[1
]}

Hitzenberger, C ^{[1
]}

Wojtkowski, M ^{[1
]}

Bajraszewski, T ^{[1
]}

Fercher, AF ^{[1
]}

机构：

[1] Univ Vienna, Dept Phys Med, A-1090 Vienna, Austria

来源：

COHERENCE DOMAIN OPTICAL METHODS AND OPTICAL COHERENCE TOMOGRAPHY IN BIOMEDICINE VIII | 2004年 / 5316卷

关键词：

optical coherence tomography; Fourier domain; spectral domain; partial coherence interferometry; laser Doppler velocimetry;

D O I：

10.1117/12.531327

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We realized an in vivo Fourier domain optical coherence tomography (FD OCT) setup that allows acquiring retinal depth scans at a rate of 25.000 per second. We demonstrate the possibility to measure Doppler flow depth profile in specific regions of interest. The method to extract the flow profiles is based on a local phase analysis of the backscattered signal and allows for bidirectional Doppler flow imaging. The velocity resolution in tissue is 200mum/s. We verified the method by measuring pump controlled in vitro flow through a glass capillary. The system allows for a real-time colour encoded Doppler tomogram rate of 2-4 per second. We recorded the pulsatility of different vessels close to optic nerve head.

引用

页码：141 / 146

页数：6

共 19 条

[1] Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography [J].