Selective oestrogen receptor modulation: Molecular pharmacology for the millennium

被引：120

作者：

Levenson, AS ^{[1
]}

Jordan, VC ^{[1
]}

机构：

[1] Northwestern Univ, Sch Med, Robert H Lurie Comprehens Canc Ctr, Chicago, IL 60611 USA

来源：

EUROPEAN JOURNAL OF CANCER | 1999年 / 35卷 / 12期

关键词：

tamoxifen; raloxifene; breast cancer; prevention;

D O I：

10.1016/S0959-8049(99)00183-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1628 / 1639

页数：12

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