Population structure of Francisella tularensis

被引：36

作者：

Nuebel, Ulrich

Reissbrodt, Rolf

Weller, Annette

Grunow, Roland

Porsch-Oezcueruemez, Mustafa

Tomaso, Herbert

Hofer, Erwin

Splettstoesser, Wolf

Finke, Ernst-Juergen

Tschaepe, Helmut

Witte, Wolfgang

机构：

[1] Robert Koch Inst, D-38855 Wernigerode, Germany

[2] Bundeswehr Inst Microbiol, Munich, Germany

[3] Austrian Agcy Hlth & Food Safety, Modling, Austria

[4] Univ Hosp, Dept Microbiol, Rostock, Germany

来源：

JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 14期

关键词：

D O I：

10.1128/JB.01662-05

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have sequenced fragments of five metabolic housekeeping genes and two genes encoding outer membrane proteins from 81 isolates of Francisella tularensis, representing all four subspecies. Phylogenetic clustering of gene sequences from F. tularensis subsp. tularensis and F. tularensis subsp. holarctica aligned well with subspecies affiliations. In contrast, F. tularensis subsp. novicida and F. tularensis subsp. mediasiatica were indicated to be phylogenetically incoherent taxa. Incongruent gene trees and mosaic structures of housekeeping genes provided evidence for genetic recombination in F. tularensis.

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收藏

页码：5319 / 5324

页数：6

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