A case of azoospermia in a bull carrying a Y-autosome reciprocal translocation

被引：33

作者：

Iannuzzi, L

Molteni, L

Di Meo, GP

De Giovanni, A

Perucatti, A

Succi, G

Incarnato, D

Eggen, A

Cribiu, EP

机构：

[1] CNR, IABBAM, Lab Anim Cytogenet & Gene Mapping, Naples, Italy

[2] Agr Fac Sci, Inst Anim Sci, Milan, Italy

[3] INRA, Dept Anim Genet, Lab Biochem Genet & Cytogenet, Jouy En Josas, France

来源：

CYTOGENETICS AND CELL GENETICS | 2001年 / 95卷 / 3-4期

关键词：

D O I：

10.1159/000059349

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During normal cytogenetic investigations on the Chianina cattle (BTA) breed, a normal looking young bull was found to carry an abnormal Y chromosome which was a product of a reciprocal translocation between chromosomes Y and 9. This was revealed by both CBA- and RBG-banding techniques and was clearly confirmed by FISH-mapping analysis with IDVGA50 (which paints the complete Yq arm in a normal Y), as well as with AMD1, CGA, IGF2R (mapping to BTA9q16. BTA9q22 and BTA9q27 --> q28, respectively) and SRY (mapping to normal BTAYq23). Analysis on sperm from four different samples revealed azoospermia in the carrier, indicating that the rcp(Y;9) induces sterility in the bull. Copyright (C) 2002 S. Karger AG, Basel.

引用

页码：225 / 227

页数：3