Lymphoplasmacytic lymphoma exposed by haemoptysis and acquired von Willebrand syndrome

被引：5

作者：

Coucke, Line ^{[1
]}

Marcelis, Ludo ^{[2
]}

Deeren, Dries ^{[3
]}

Van Dorpe, Jo ^{[4
]}

Lambein, Kathleen ^{[5
]}

Devreese, Katrien ^{[1
]}

机构：

[1] Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Coagulat Lab, Ghent, Belgium

[2] AZ Delta Hosp, Clin Lab, Roeselare, Belgium

[3] AZ Delta Hosp, Roeselare, Belgium

[4] AZ Delta Hosp, Dept Pathol, Roeselare, Belgium

[5] Ghent Univ Hosp, Dept Pathol, Ghent, Belgium

来源：

BLOOD COAGULATION & FIBRINOLYSIS | 2014年 / 25卷 / 04期

关键词：

Waldenstrom macroglobulinaemia; non-Hodgkin lymphoma; von Willebrand factor; haemoptysis; acquired von Willebrand syndrome;

D O I：

10.1097/MBC.0000000000000052

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report on a 36-year-old man who presented to the emergency department with haemoptysis. Computed tomography (CT) of the thorax showed a pulmonary mass paramediastinal in the right upper lobe, with the density of a haematoma. Laboratory data demonstrated an absolute lymphocytosis of 5.900 x 10(9)/l (normal range, 1.150-3.250 x 10(9)/l) and a prolonged activated partial thromboplastin time (APTT) of 47.7 s (normal range, 28.0-39.0 s). A de novo diagnosis of lymphoplasmacytic lymphoma (Waldenstrom macroglobulinaemia) was made, complicated by an acquired von Willebrand syndrome (aVWS) as demonstrated by further laboratory investigations. In this case report, we present a case of aVWS with markedly prolonged APTT and haemoptysis that revealed an underlying Waldenstrom macroglobulinaemia.

引用

页码：395 / 397

页数：3

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