Infrared spectroscopic mapping of single nanoparticles and viruses at nanoscale resolution

被引:202
作者
Brehm, Markus
Taubner, Thomas
Hillenbrand, Rainer
Keilmann, Fritz [1 ]
机构
[1] Max Planck Inst Biochem, D-82152 Munich, Germany
[2] Ctr Nanosci, D-82152 Munich, Germany
关键词
D O I
10.1021/nl0610836
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We demonstrate that scattering near-field microscopy (s-SNOM) can determine infrared "fingerprint" spectra of individual poly( methyl methacrylate) nanobeads and viruses as small as 18 nm. Amplitude and phase spectra are found surprisingly strong, even at a probed volume of only 10(-20) l, and robust in regard to particle size and substrate. This makes infrared spectroscopic s-SNOM a versatile tool for chemical and-in the case of protein-secondary-structure identification.
引用
收藏
页码:1307 / 1310
页数:4
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