CHEM21 selection guide of classical- and less classical-solvents

被引:1646
作者
Prat, Denis [1 ]
Wells, Andy [2 ]
Hayler, John [3 ]
Sneddon, Helen [3 ]
McElroy, C. Robert [4 ]
Abou-Shehada, Sarah [4 ]
Dunn, Peter J. [5 ]
机构
[1] Sanofi Aventis Res & Dev, F-94403 Vitry Sur Seine, France
[2] Charnwood Tech Consulting, Quorn LE12 8AT, Leics, England
[3] GlaxoSmithKline Med Res Ctr, Stevenage SG1 2NY, Herts, England
[4] Univ York, Green Chem Ctr Excellence, York YO10 5DD, N Yorkshire, England
[5] Pfizer Global Supply, Sandwich CT13 9NJ, Kent, England
关键词
CYCLOPENTYL METHYL-ETHER; BIO-DERIVED SOLVENTS; DESIGN; GENERATION; CHEMISTRY; FRAMEWORK; TOXICITY; METHANOL; GAS;
D O I
10.1039/c5gc01008j
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
A selection guide of common solvents has been elaborated, based on a survey of publically available solvent selection guides. In order to rank less classical solvents, a set of Safety, Health and Environment criteria is proposed, aligned with the Global Harmonized System (GHS) and European regulations. A methodology based on a simple combination of these criteria gives an overall preliminary ranking of any solvent. This enables in particular a simplified greenness evaluation of bio-derived solvents.
引用
收藏
页码:288 / 296
页数:9
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