Pyranoquinoline alkaloids from Zanthoxylum simulans

被引：122

作者：

Chen, IS

Tsai, IW

Teng, CM

Chen, JJ

Chang, YL

Ko, FN

Lu, MC

Pezzuto, JM

机构：

[1] NATL TAIWAN UNIV,COLL MED,INST PHARMACOL,TAIPEI,TAIWAN

[2] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,CHICAGO,IL

来源：

PHYTOCHEMISTRY | 1997年 / 46卷 / 03期

关键词：

Zanthoxylum simulans; Rutaceae; bark; alkaloids; pyranoquinoline; simulenoline; peroxysimulenoline; benzosimuline; zanthodioline; anti-platelet aggregation activity;

D O I：

10.1016/S0031-9422(97)00280-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three new pyranoquinoline alkaloids, simulenoline, peroxysimulenoline and benzosimuline, together with 22 known compounds, were isolated from the stem bark of Formosan Zanthoxylum simulans. Structures including zanthodioline, a known alkaloid without published data, were elucidated by spectral evidences. Among the isolates, 14 compounds showed strong anti-platelet aggregation activity in vitro. (C) 1997 Elsevier Science Ltd.

引用

页码：525 / 529

页数：5

共 20 条

[1] TRITERPENOID KETONES FROM LINGNANIA-CHUNGII MCCLURE - ARBORINONE, FRIEDELIN AND GLUTINONE [J].

AKIHISA, T ;

YAMAMOTO, K ;

TAMURA, T ;

KIMURA, Y ;

IIDA, T ;

NAMBARA, T ;

CHANG, FC .

CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, 40 (03) :789-791

[2] ALKYL FERULATES IN WOUND-HEALING POTATO-TUBERS [J].

BERNARDS, MA ;

LEWIS, NG .

PHYTOCHEMISTRY, 1992, 31 (10) :3409-3412

[3]

BROWEN IH, 1978, PHYGOCHEISTRY, V17, P2125

[4] Hydroperoxycycloartanes from Tillandsia recurvata [J].

Cabrera, GM ;

Seldes, AM .

JOURNAL OF NATURAL PRODUCTS, 1995, 58 (12) :1920-1924

[5]

CHEN IS, 1994, PHYTOCHEMISTRY, V36, P237, DOI 10.1016/S0031-9422(00)97045-6

[6]

Chen IS, 1996, PHYTOCHEMISTRY, V42, P217, DOI 10.1016/0031-9422(95)00856-X

[7] CHEMICAL AND BIOACTIVE CONSTITUENTS FROM ZANTHOXYLUM SIMULANS [J].

CHEN, IS ;

WU, SJ ;

TSAI, IL ;

WU, TS ;

PEZZUTO, JM ;

LU, MC ;

CHAI, H ;

SUH, N ;

TENG, CM .

JOURNAL OF NATURAL PRODUCTS, 1994, 57 (09) :1206-1211

[8]

GALEN WE, 1946, J AM CHEM SOC, V68, P2181

[9]

GRAY AI, 1983, CHEM CHEM TAXONOMY R, P54

[10] STUDIES ON THE CHEMICAL-CONSTITUENTS OF RUTACEOUS PLANTS .44. THE CHEMICAL-CONSTITUENTS OF XANTHOXYLUM-INTEGRIFOLIOLUM (MERR) MERR (FAGARA-INTEGRIFOLIOLA MERR) .1. THE CHEMICAL-CONSTITUENTS OF THE ROOT WOOD [J].

ISHII, H ;

CHEN, IS ;

AKAIKE, M ;

ISHIKAWA, T ;

LU, ST .

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1982, 102 (02) :182-195

← 1 2 →