Perspectives on the role of ultrasonic devices in thrombolysis

被引:28
作者
Atar, S
Rosenschein, U
机构
[1] Bnai Zion Med Ctr, IL-31048 Haifa, Israel
[2] HaEmek Med Ctr, Afula, Israel
关键词
ultrasonic devices; ultrasound; thrombolysis;
D O I
10.1023/B:THRO.0000037665.21691.61
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Reperfusion strategies in acute myocardial infarction and thrombotic vascular occlusion are focused on rapid and complete restoration of antegrade flow in the infarct-related artery in order to maximize myocardial salvage. Due to the limitations of fibrinolytic agents in restoration of vascular flow, ultrasonic clot dissolution alone and concomitantly with fibrinolytic, anti-thrombotic and echocardiographic contrast agents has been intensively studied during the last 2 decades. Ultrasound thrombolysis has been tested in-vitro and in-vivo as well as in patients with acute thrombotic occlusions. We review currently available techniques and methods of ultrasonic thrombolysis and present recent clinical and experimental data. The future role of ultrasonic thrombolysis and the strategy of "power thrombectomy" for treatment of acute coronary syndromes is also discussed.
引用
收藏
页码:107 / 114
页数:8
相关论文
共 34 条
[11]   Intravascular therapeutic ultrasound thrombolysis in acute myocardial infarctions [J].
Hamm, CW ;
Steffen, W ;
Terres, W ;
deScheerder, I ;
Reimers, J ;
Cumberland, D ;
Siegel, RJ ;
Meinertz, T .
AMERICAN JOURNAL OF CARDIOLOGY, 1997, 80 (02) :200-204
[12]   ULTRASOUND ACCELERATES UROKINASE-INDUCED THROMBOLYSIS AND REPERFUSION [J].
HARPAZ, D ;
CHEN, XC ;
FRANCIS, CW ;
MELTZER, RS .
AMERICAN HEART JOURNAL, 1994, 127 (05) :1211-1219
[13]  
KUDO S, 1989, Tokyo Jikeikai Medical Journal, V104, P1005
[14]   EFFECT OF ULTRASOUND ON TISSUE-TYPE PLASMINOGEN-ACTIVATOR INDUCED THROMBOLYSIS [J].
LAUER, CG ;
BURGE, R ;
TANG, DB ;
BASS, BG ;
GOMEZ, ER ;
ALVING, BM .
CIRCULATION, 1992, 86 (04) :1257-1264
[15]   Transcutaneous ultrasound augments lysis of arterial thrombi in vivo [J].
Luo, H ;
Nishioka, T ;
Fishbein, MC ;
Cercek, B ;
Forrester, JS ;
Kim, CJ ;
Berglund, H ;
Siegel, RJ .
CIRCULATION, 1996, 94 (04) :775-778
[16]   ENHANCEMENT OF THROMBOLYSIS BY EXTERNAL ULTRASOUND [J].
LUO, H ;
STEFFEN, W ;
CERCEK, B ;
ARUNASALAM, S ;
MAURER, G ;
SIEGEL, RJ .
AMERICAN HEART JOURNAL, 1993, 125 (06) :1564-1569
[17]   Enhancement of thrombolysis in vitro without skin and soft tissue damage by transcutaneous ultrasound [J].
Luo, H ;
Birnbaum, Y ;
Fishbein, MC ;
Peterson, TM ;
Nagai, T ;
Nishioka, T ;
Siegel, RJ .
THROMBOSIS RESEARCH, 1998, 89 (04) :171-177
[18]  
LUO H, 1986, J THROMB THROMBOLYS, V6, P125
[19]   Dissolution of thrombotic arterial occlusion by high intensity, low frequency ultrasound and dodecafluoropentane emulsion: An in vitro and in vivo study [J].
Nishioka, T ;
Luo, H ;
Fishbein, MC ;
Cercek, B ;
Forrester, JS ;
Kim, CJ ;
Berglund, H ;
Siegel, RJ .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 30 (02) :561-568
[20]   Ultrasound, microbubbles, and thrombolysis [J].
Porter, TR ;
Xie, F .
PROGRESS IN CARDIOVASCULAR DISEASES, 2001, 44 (02) :101-110