Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi

被引：51

作者：

Mita, T

Kaneko, A

Lum, JK

Zungu, IL

Tsukahara, T

Eto, H

Kobayakawa, T

Björkman, A

Tanabe, K

机构：

[1] Tokyo Womens Med Univ, Sch Med, Dept Int Affairs & Trop Med, Shinjuku Ku, Tokyo 1628666, Japan

[2] Karolinska Hosp, Karolinska Inst, Malaria Res Lab, S-17176 Stockholm, Sweden

[3] SUNY Binghamton, Dept Anthropol, Binghamton, NY 13902 USA

[4] Minist Hlth & Populat, Community Hlth Sci unit, Lilongwe, Malawi

[5] Osaka Inst Technol, Biol Lab, Osaka 5358585, Japan

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 2004年 / 135卷 / 01期

关键词：

Plasmodium falciparum; chloroquine; pfcrt; pfmdr1; back mutation;

D O I：

10.1016/j.molbiopara.2004.01.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

[No abstract available]

引用

页码：159 / 163

页数：5

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