Two new monodesmosidic triterpene saponins from Gypsophila oldhamiana

被引：24

作者：

Luo, Jian-Guang

Kong, Ling-Yi

Takaya, Yoshiaki

Niwa, Masatake

机构：

[1] China Pharmaceut Univ, Dept Nat Med Chem, Nanjing 210009, Peoples R China

[2] Meijo Univ, Fac Pharm, Tempa Ku, Nagoya, Aichi 4688503, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2006年 / 54卷 / 08期

关键词：

Gypsophila oldhamiana; Caryophyllaceae; triterpenoid saponin; quillaic acid; vaccaric acid; immunologic activity;

D O I：

10.1248/cpb.54.1200

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Two new monodesmosidic triterpene saponins were isolated from the roots of Gypsophila oldhamiana (Caryophyllaceae). Their structures were elucidated on the basis of spectral data to be quillaic acid, alpha-L-arabinopyranosyl-(1 -> 4)-alpha-L-arabinopyranosyl-(1 -> 3)-[beta-D-Xylopyranosyl-(1 -> 4)-beta-L-rhamnopyranosyl-(1 -> 2)-beta-D-fucopyranosyl ester (1), and vaccaric acid, beta-D-glucopyranosyl-(1 -> 3)-[beta-D-xylopyranosyl-(1 -> 4)]-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-fucopyranosyl ester (2). Compound 1 showed a significant enhancement of granulocyte phagocytosis in vitro.

引用

页码：1200 / 1202

页数：3

共 17 条

[1]

[Anonymous], 1977, CHINESE MED DICT, P2170

[2]

4 TRITERPENOID SAPONINS FROM DRIED ROOTS OF GYPSOPHILA SPECIES [J].