共 23 条
Bridgehead enolates and bridgehead alkenes in a welwistatin model series
被引:22
作者:
Boissel, Valerie
[2
]
Simpkins, Nigel S.
[2
]
Bhalay, Gurdip
[1
]
Blake, Alexander J.
[2
]
Lewis, William
[2
]
机构:
[1] Horsham Res Ctr, Novartis Inst Biomed Res, Global Discovery Chem, Horsham, W Sussex, England
[2] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England
关键词:
SKELETON;
WELWITINDOLINONES;
CLUSIANONE;
EFFICIENT;
D O I:
10.1039/b820674k
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Bridgehead metallation is possible in a ketone having the welwistatin skeleton, and this facilitates installation of the isothiocyanate function present in the natural product, and also enables synthesis of remarkable bridgehead alkenes.
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页码:1398 / 1400
页数:3
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