Innate recognition systems in insect immunity and development:: new approaches in Drosophila

被引:38
作者
Franc, NC [1 ]
White, K [1 ]
机构
[1] Harvard Univ, Massachusetts Gen Hosp, Cutaneous Biol Res Ctr, Sch Med,Dept Dermatol, Charlestown, MA USA
关键词
insect; immunity; recognition; phagocytosis; lectin;
D O I
10.1016/S1286-4579(00)00304-X
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Phagocytosis is important in immune defense and development in vertebrates and invertebrates. It leads to swift ingestion of microorganisms and dying cells by phagocytes. How particles are recognized is not well understood. Studies in insects, and Drosophila in particular, argue that these are powerful model systems to dissect this process. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:243 / 250
页数:8
相关论文
共 97 条
  • [1] MACROPHAGES IN DROSOPHILA EMBRYOS AND L2 CELLS EXHIBIT SCAVENGER RECEPTOR-MEDIATED ENDOCYTOSIS
    ABRAMS, JM
    LUX, A
    STELLER, H
    KRIEGER, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (21) : 10375 - 10379
  • [2] THE SPECIFIC RECOGNITION BY MACROPHAGES OF CD8(+),CD45RO(+) T-CELLS UNDERGOING APOPTOSIS - A MECHANISM FOR T-CELL CLEARANCE DURING RESOLUTION OF VIRAL-INFECTIONS
    AKBAR, AN
    SAVILL, J
    GOMBERT, W
    BOFILL, M
    BORTHWICK, NJ
    WHITELAW, F
    GRUNDY, J
    JANOSSY, G
    SALMON, M
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 180 (05) : 1943 - 1947
  • [3] Cloning of cDNA for regenectin, a humoral C-type lectin of Periplaneta americana, and expression of the regenectin gene during leg regeneration
    Arai, T
    Kawasaki, K
    Kubo, T
    Natori, S
    [J]. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1998, 28 (12) : 987 - 994
  • [4] ASHIDA M, 1990, RES IMMUNOL, V141, P908, DOI 10.1016/0923-2494(90)90191-Z
  • [5] A conserved signaling pathway: The Drosophila Toll-Dorsal pathway
    Belvin, MP
    Anderson, KV
    [J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1996, 12 : 393 - 416
  • [6] Bernardoni R, 1997, DEV BIOL, V191, P118
  • [7] Cell adhesion properties of hemolin, an insect immune protein in the Ig superfamily
    Bettencourt, R
    Lanz-Mendoza, H
    Lindquist, KR
    Faye, I
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 250 (03): : 630 - 637
  • [8] SEVERE HERPESVIRUS INFECTIONS IN AN ADOLESCENT WITHOUT NATURAL-KILLER CELLS
    BIRON, CA
    BYRON, KS
    SULLIVAN, JL
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (26) : 1731 - 1735
  • [9] C1q knock-out mice for the study of complement deficiency in autoimmune disease
    Botto, M
    [J]. EXPERIMENTAL AND CLINICAL IMMUNOGENETICS, 1998, 15 (04) : 231 - 234
  • [10] Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
    Botto, M
    Dell'Agnola, C
    Bygrave, AE
    Thompson, EM
    Cook, HT
    Petry, F
    Loos, M
    Pandolfi, PP
    Walport, MJ
    [J]. NATURE GENETICS, 1998, 19 (01) : 56 - 59