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An exfoliative toxin A-converting phage isolated from Staphylococcus aureus strain ZM

被引：30
作者：
Yoshizawa, Y
Sakurada, J
Sakurai, S
Machida, K
Kondo, I
Masuda, S
机构：
[1] Jikei Univ, Sch Med, Radioisotope Res Ctr, Minato Ku, Tokyo 1058461, Japan
[2] Jikei Univ, Sch Med, Dept Microbiol 2, Minato Ku, Tokyo 1058461, Japan
[3] Jikei Univ, Sch Med, Dept Lab Med, Minato Ku, Tokyo 1058461, Japan
[4] Kohno Clin Med Res Inst, Dept Mol Genet, Shinagawa Ku, Tokyo 1400001, Japan
来源：
MICROBIOLOGY AND IMMUNOLOGY | 2000年 / 44卷 / 03期
关键词：
staphylococcal scalded skin-syndrome; exfoliative toxin; phage conversion;
D O I：
10.1111/j.1348-0421.2000.tb02481.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Exfoliative toxin A (ETA) causes staphylococcal scalded-skin syndrome in children, The gene for ETA was believed to be coded by the chromosomal DNA. We isolated temperate phages from an ETA-producing strain, ZM, using a restriction minus strain, 1039, as an indicator. One of the prophages, designated phi-ZM-1 mediated lysogenic conversion of ETA. The polymerase chain reaction assay of the eta gene revealed that phage phi-ZM-1 carries the structural gene for ETA.
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页码：189 / 191
页数：3
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