Role of adipose tissue as an inflammatory organ in human diseases

被引：193

作者：

Schaeffler, A.

Mueller-Ladner, U.

Schoelmerich, J.

Buechler, C.

机构：

[1] Univ Regensburg, Dept Internal Med 1, D-93042 Regensburg, Germany

[2] Univ Giessen, Dept Rheumatol & Clin Immunol, D-61231 Giessen, Germany

来源：

ENDOCRINE REVIEWS | 2006年 / 27卷 / 05期

关键词：

D O I：

10.1210/er.2005-0022

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Reviews on the inflammatory role of adipose tissue outside the field of metabolism are rare. There is increasing evidence provided by numerous basic research studies from nearly all internal medicine subspecializations that adipocytes and adipocytokines are involved in primary inflammatory processes and diseases. Therefore, it is the aim of the present review to discuss and to summarize the current knowledge on the inflammatory role of adipocytokines and special types of regional adipocytes such as retroorbital, synovial, visceral, subdermal, peritoneal, and bone marrow adipocytes in internal medicine diseases. Future clinical and therapeutic implications are discussed.

引用

页码：449 / 467

页数：19

共 285 条

[51] Role of peroxisome proliferator-activated receptor γ and retinoid X receptor heterodimer in hepatogastroenterological diseases [J].

Dubuquoy, L ;

Dharancy, S ;

Nutten, S ;

Pettersson, S ;

Auwerx, J ;

Desreumaux, P .

LANCET, 2002, 360 (9343) :1410-1418

[52] Evidence for a key role of leptin in osteoarthritis [J].

Dumond, H ;

Presle, N ;

Terlain, B ;

Mainard, D ;

Loeuille, D ;

Netter, P ;

Pottie, P .

ARTHRITIS AND RHEUMATISM, 2003, 48 (11) :3118-3129

[53]

Ehling A, 2003, ARTHRITIS RHEUM, V48, pS477

[54]

EHLING A, 2004, EXP CLIN ENDOCRINOL, V112, P19

[55] The potential of adiponectin in driving arthritis [J].

Ehling, Angela ;

Schaeffler, Andreas ;

Herfarth, Hans ;

Tarner, Ingo H. ;

Anders, Sven ;

Distler, Oliver ;

Paul, Gisela ;

Distler, Joerg ;

Gay, Steffen ;

Schoelmerich, Jurgen ;

Neumann, Elena ;

Mueller-Ladner, Ulf .

JOURNAL OF IMMUNOLOGY, 2006, 176 (07) :4468-4478

[56] Leptin regulation of bone resorption by the sympathetic nervous system and CART [J].

Elefteriou, F ;

Ahn, JD ;

Takeda, S ;

Starbuck, M ;

Yang, XL ;

Liu, XY ;

Kondo, H ;

Richards, WG ;

Bannon, TW ;

Noda, M ;

Clement, K ;

Vaisse, C ;

Karsenty, G .

NATURE, 2005, 434 (7032) :514-520

[57] Sclerosing mesenteritis, mesenteric panniculitis and mesenteric lipodystrophy: A single entity? [J].

Emory, TS ;

Monihan, JM ;

Carr, NJ ;

Sobin, LH .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1997, 21 (04) :392-398

[58] Induction of leptin expression in orbital preadipocyte fibroblasts [J].

Erickson, DZ ;

Harteneck, DA ;

Erickson, BJ ;

Dutton, CM ;

Bahn, RS .

THYROID, 2001, 11 (03) :221-226

[59]

Esterbauer H, 1999, EUR J CLIN INVEST, V29, P653

[60] Serum leptin concentration is increased in patients with Behcet's syndrome and is correlated with disease activity [J].

Evereklioglu, C ;

Inalöz, HS ;

Kirtak, N ;

Doganay, S ;

Bülbül, M ;

Otlu, B ;

Özerol, E ;

Er, H ;

Özbek, E .

BRITISH JOURNAL OF DERMATOLOGY, 2002, 147 (02) :331-336

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