Ring closure metathesis of indole 2-carboxylic acid allylamide derivatives

被引：25

作者：

Chacun-Lefèvre, L ^{[1
]}

Bénéteau, V ^{[1
]}

Joseph, B ^{[1
]}

Mérour, JY ^{[1
]}

机构：

[1] Univ Orleans, CNRS, Inst Chim Organ & Analyt, UMR 6005, F-45067 Orleans 2, France

来源：

TETRAHEDRON | 2002年 / 58卷 / 51期

关键词：

indole; cyclisation; lactam; ruthenium metathesis;

D O I：

10.1016/S0040-4020(02)01404-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring-closing metathesis of 3-allyl- or 3-vinylindole-2-carboxylic derivatives gave access to fused seven- to eight-membered lactams; 1-allylindole-2-carboxylic homoallylamide afforded the nine-membered lactam. The reactivity of 1,3-disubstituted-2-carboxylic acid derivatives was also investigated. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：10181 / 10188

页数：8

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