Panic attacks, daily life ischemia, and chest pain in postmenopausal women

被引:6
作者
Smoller, Jordan W.
Pollack, Mark H.
Wassertheil-Smoller, Sylvia
Brunner, Robert
Curb, David
Torner, James
Oberman, Albert
Hendrix, Susan L.
Hsia, Judith
Sheps, David S.
机构
[1] Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA
[2] Albert Einstein Coll Med, Bronx, NY 10467 USA
[3] Univ Nevada, Sch Med, Reno, NV 89557 USA
[4] Univ Hawaii, Honolulu, HI 96822 USA
[5] Univ Iowa, Iowa City, IA USA
[6] Univ Alabama Birmingham, Dept Med, Birmingham, AL 35294 USA
[7] Wayne State Univ, Dept Obstet & Gynecol, Hutzel Womens Hosp, Detroit, MI USA
[8] George Washington Univ, Med Ctr, Washington, DC 20037 USA
[9] Univ Florida, Gainesville, FL USA
[10] Malcom Randall VA Med Ctr, Gainesville, FL USA
来源
PSYCHOSOMATIC MEDICINE | 2006年 / 68卷 / 06期
关键词
daily life ischemia; postmenopausal women; panic; chest pain; panic disorder;
D O I
10.1097/01.psy.0000244383.19453.c5
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Chest pain is a common symptom of panic attacks, but little is known about the relationship in older women among panic attacks, chest pain, and daily life ischemia. Methods: The authors conducted a cross-sectional survey of 3063 community-dwelling, generally healthy postmenopausal women enrolled between 1997 and 2000 in the Myocardial Ischemia and Migraine Study in 10 clinical centers of the 40-center Women's Health Initiative. Participants, ages 50 to 79 years, completed a questionnaire about occurrence of panic attacks in the previous 6 months and underwent 24-hour ambulatory electrocardiogram monitoring (AECG); 2705 women had valid AECG recordings and panic attack questionnaires. ST depression on AECG, heart rate variability (HRV), and chest pain episodes were compared among women with and without a 6-month history of panic attack. Results: There was no difference in overall prevalence of ischemic episodes during AECG between women with and without panic attacks. Women with a recent history of panic were more likely to experience chest pain during AECG after controlling for potential confounders (odds ratio [OR] = 2.01; 95% confidence interval [CI] 1.40-2.88), including both nonischemic (OR = 1.83; 95% Cl = 1.26-2.65) and ischemic chest pain (OR = 4.94; 95% Cl 1.41-17.30). Although mean HRV was lower in those with panic attacks (p =.0 17), this was not significant after controlling for confounders. Conclusions: Postmenopausal women with a recent history of panic attacks do not appear to have more daily life ischemia as measured by occurrence of ST depression during 24-hour monitoring, but do have more chest pain and possibly lower HRV, suggesting that even sporadic panic attacks may be related to cardiovascular risk.
引用
收藏
页码:824 / 832
页数:9
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