Virulence genes in Helicobacter pylori strains from West Bengal residents with overt H-pylori-associated disease and healthy volunteers

被引：42

作者：

Chattopadhyay, S

Datta, S

Chowdhury, A

Chowdhury, S

Mukhopadhyay, AK

Rajendran, K

Bhattacharya, SK

Berg, DE

Nair, GB

机构：

[1] Natl Inst Cholera & Enter Dis, Kolkata 700010, W Bengal, India

[2] Postgrad Inst Med Educ & Res, Dept Gastroenterol, Kolkata, W Bengal, India

[3] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA

[4] Int Ctr Diarrhoeal Dis Res, Dhaka 1000, Bangladesh

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 07期

关键词：

D O I：

10.1128/JCM.40.7.2622-2625.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We compared putative molecular markers of virulence (vacA, cag4, and iceA) of Helicobacter pylori strains isolated from 52 adult duodenal ulcer patients from West Bengal, India, with those of H.pylori strains isolated from 48 adult healthy volunteers from the same region. On the basis of genotyping by PCR, we conclude that the H. pylori strains isolated from the two study groups were indistinguishable and that there are geographic variations in the association of certain putative H. pylori virulence genes with clinical status.

引用

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页码：2622 / 2625

页数：4

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