Unzipping of DNA with correlated base sequence

被引:12
作者
Allahverdyan, AE
Gevorkian, ZS
Hu, CK
Wu, MC
机构
[1] Inst Theoret Phys, NL-1018 XE Amsterdam, Netherlands
[2] Yerevan Phys Inst, Yerevan 375036, Armenia
[3] Acad Sinica, Inst Phys, Taipei 11529, Taiwan
[4] Inst Radiophys & Elect, Ashtarak 378410 2, Armenia
来源
PHYSICAL REVIEW E | 2004年 / 69卷 / 06期
关键词
D O I
10.1103/PhysRevE.69.061908
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We consider force-induced unzipping transition for a heterogeneous DNA model with a correlated base sequence. Both finite-range and long-range correlated situations are considered. It is shown that finite-range correlations increase stability of DNA with respect to the external unzipping force. Due to long-range correlations the number of unzipped base pairs displays two widely different scenarios depending on the details of the base sequence: either there is no unzipping phase transition at all, or the transition is realized via a sequence of jumps with magnitude comparable to the size of the system. Both scenarios are different from the behavior of the average number of unzipped base pairs (non-self-averaging). The results can be relevant for explaining the biological purpose of correlated structures in DNA.
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页数:16
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