The red cell storage lesion and its implication for transfusion

被引：130

作者：

ChinYee, I ^{[1
]}

Arya, N ^{[1
]}

dAlmeida, MS ^{[1
]}

机构：

[1] UNIV WESTERN ONTARIO, FAC MED, LONDON, ON N6A 3K7, CANADA

来源：

TRANSFUSION SCIENCE | 1997年 / 18卷 / 03期

关键词：

D O I：

10.1016/S0955-3886(97)00043-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Storage of red blood cells in preservative medium is associated with metabolic, biochemical and molecular changes to erythrocytes collectively referred to as the ''storage lesion.'' In addition to corpuscular injury, bioreactive substances including cytokines and lipids accumulate in the medium during storage. We review evidence for those storage related changes and potential clinical implications for red blood cell transfusion. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：447 / 458

页数：12

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