Chemotherapeutic neuropathy

被引：66

作者：

Windebank, AJ ^{[1
]}

机构：

[1] Mayo Med Ctr, Rochester, MN 55905 USA

来源：

CURRENT OPINION IN NEUROLOGY | 1999年 / 12卷 / 05期

关键词：

D O I：

10.1097/00019052-199910000-00010

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Peripheral neurotoxicity is a dose-limiting side-effect for a number of effective chemotherapeutic agents, including platinum compounds, taxanes, and vinca alkaloids. New experimental chemotherapy drugs that cause neuropathy include suramin and Dolostatin-10. A better understanding of cellular mechanisms will lead to novel treatment strategies that will protect neurons without decreasing therapeutic efficacy. Curr Opin Neurol 12:565-571. (C) 1999 Lippincott Williams & Wilkins.

引用

页码：565 / 571

页数：7

共 77 条

[71] Programmed cell death in neurotumour cells involves the generation of ceramide [J].