Circulating IL-6 and sIL-6R in patients with hepatocellular carcinoma

被引：52

作者：

Giannitrapani, L

Cervello, M

Soresi, M

Notarbartolo, M

La Rosa, M

Virruso, L

D'Alessandro, N

Montalto, G ^{[1
]}

机构：

[1] Univ Palermo, Ist Med Interna & Geriatria, Palermo, Italy

[2] CNR, Ist Biol Sviluppo, Palermo, Italy

[3] Univ Palermo, Dipartimento Sci Farmacol, Palermo, Italy

来源：

HORMONE-RELATED TUMORS: NOVEL APPROACHES TO PREVENTION AND TREATMENT | 2002年 / 963卷

关键词：

hepatocellular carcinoma; interleukin-6; signal transduction protein; gp130; liver function tests; receptor;

D O I：

10.1111/j.1749-6632.2002.tb04093.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Interleukin-6 plays a central role in regulating the immune system, hematopoiesis, and acute phase reaction. It interacts with a receptor complex consisting of a specific ligand-binding protein (IL-6R, gp80) and a signal transduction protein (gp130). In this report, serum levels of IL-6 and a soluble form of the interleukin-6 receptor (sIL-6R) were evaluated in patients with hepatocellular carcinoma. The correlation between IL-6 and sIL-6R values, the stage of hepatocellular carcinoma, and main liver function tests was also studied.

引用

页码：46 / 52

页数：7

共 20 条

[1] SERUM INTERLEUKIN-6 LEVELS CORRELATE WITH DISEASE STATUS IN PATIENTS WITH EPITHELIAL OVARIAN-CANCER [J].