The canonical Wnt pathway in embryonic axis polarity

被引：52

作者：

Croce, Jenifer C. ^{[1
]}

McClay, David R. ^{[1
]}

机构：

[1] Duke Univ, Dev Cell & Mol Biol Grp, Durham, NC 27708 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2006年 / 17卷 / 02期

关键词：

Wnt signaling; embryonic axes; sea urchin; Xenopus;

D O I：

10.1016/j.semcdb.2006.04.004

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The canonical Wnt pathway plays crucial roles in multiple developmental processes, including in axis specification. Throughout the animal kingdom, this pathway has been reported to drive patterning of axes as different as the animal-vegetal axis in echinoderms to the dorsal-ventral axis in vertebrates. Intriguingly enough, this pathway appears structurally and functionally well conserved during evolution. However, differences between these phyla are observed that explain how a same pathway can mediate establishment of two such apparently distinct axes. This review compares the axis specification processes used in two evolutionarily distant embryos, the sea urchin and Xenopus. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：168 / 174

页数：7

共 70 条

[1] beta-catenin is a target for the ubiquitin-proteasome pathway [J].

Aberle, H ;

Bauer, A ;

Stappert, J ;

Kispert, A ;

Kemler, R .

EMBO JOURNAL, 1997, 16 (13) :3797-3804

[2] Patterning the sea urchin embryo: Gene regulatory networks, signaling pathways, and cellular interactions [J].

Angerer, LM ;

Angerer, RC .

CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY, VOL 53, 2003, 53 :159-198

[3] Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways [J].

Axelrod, JD ;

Miller, JR ;

Shulman, JM ;

Moon, RT ;

Perrimon, N .

GENES & DEVELOPMENT, 1998, 12 (16) :2610-2622

[4] A new member of the frizzled family from Drosophila functions as a Wingless receptor [J].

Bhanot, P ;

Brink, M ;

Samos, CH ;

Hsieh, JC ;

Wang, YS ;

Macke, JP ;

Andrew, D ;

Nathans, J ;

Nusse, R .

NATURE, 1996, 382 (6588) :225-230

[5] Dishevelled: at the crossroads of divergent intracellular signaling pathways [J].

Boutros, M ;

Mlodzik, M .

MECHANISMS OF DEVELOPMENT, 1999, 83 (1-2) :27-37

[6] Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling [J].

Boutros, M ;

Paricio, N ;

Strutt, DI ;

Mlodzik, M .

CELL, 1998, 94 (01) :109-118

[7]

Boveri T., 1901, Verk. Phys-med. Ges. Wurzburg, V34, P145

[8]

Brandhorst BP, 2002, INT REV CYTOL, V213, P183

[9] Wnt signaling: a common theme in animal development [J].

Cadigan, KM ;

Nusse, R .

GENES & DEVELOPMENT, 1997, 11 (24) :3286-3305

[10] Wingless repression of Drosophila frizzled 2 expression shapes the wingless morphogen gradient in the wing [J].

Cadigan, KM ;

Fish, MP ;

Rulifson, EJ ;

Nusse, R .

CELL, 1998, 93 (05) :767-777

← 1 2 3 4 5 6 7 →