Diacetato-κ2O-bis[(S)-1-(4-fluorophenyl)ethylamine-κN]palladium(II) and di-μ-acetato-κ4O:O′-bis{[(S)-2-(1-aminoethyl)-5-fluorophenyl-κ2C1,N]palladium(II)} benzene hemisolvate

Complexes of the composition trans-[Pd(L)(2)(OAc)(2)] have been postulated as intermediates during cyclopalladation. The first structural characterization of such a precursor has now been achieved and its role in the reaction sequence has been established. Diacetato-kappa(2)O-bis[(S)-1-(4-fluorophenyl)ethylamine-kappaN]palladium(II), [Pd(O2CMe)(2)(4-FC6H3CHMe-NH2)(2)] or [Pd(C2H3O2)(2)(C8H10FN)(2)], (I), was obtained from palladium(II) acetate and (S)-NH2CHMeC6H3F-4 in a 1: 2 molar ratio. The intermediate was then reacted with additional palladium( II) acetate to give the acetate-bridged dinuclear complex di-mu-acetato-kappa(4)O:O'-bis{[(S)-2-(1-aminoethyl)-5-fluorophenyl-kappa(2)C(1),N]palladium(II)} benzene hemisolvate, [ Pd-(4-FC6H3CHMeNH2)(2)(mu-O2CMe)](2).0.5C(6)H(6) or [Pd-2(C8H9F-N)(2)(C2H3O2)(2)].0.5C(6)H(6), (II).