The synthesis of glucosinolates deuterium labelled in the glucose fragment

被引:9
作者
Robertson, Avril A. B. [1 ]
Botting, Nigel P. [1 ]
机构
[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland
关键词
glucosinolates; isothiocyanates; gluconasturtiin; cancer prevention;
D O I
10.1002/jlcr.1141
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A facile synthesis is described for 2,3,4,6-tetra-O-acetyl-thio-beta-D-[1-H-2,6-H-2(2)]glucopyranose, which has been used to make an isotopically labelled desulphoglucosinolate, [1'-H-2,6'-H-2(2)]desulfogluconasturtiln. This isotopically labelled building block can be employed to make any glucosinolate or desulfoglucosinolate for use as internal standards for MS based analytical methods. Copyright (c) 2006 John Wiley & Sons, Ltd.
引用
收藏
页码:1201 / 1211
页数:11
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