The life of lipid droplets

被引：376

作者：

Walther, Tobias C. ^{[1
]}

Farese, Robert V., Jr. ^{[2
,3
,4
]}

机构：

[1] Max Planck Inst Biochem, D-82152 Martinsried, Germany

[2] Gladstone Inst Cardiovasc Dis, San Francisco, CA USA

[3] Univ Calif San Francisco, Dept Med & Biochem, San Francisco, CA 94143 USA

[4] Univ Calif San Francisco, Dept Biophys, San Francisco, CA 94143 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 2009年 / 1791卷 / 06期

关键词：

Adiposome; Triglyceride; Steryl ester; Fat storage; Organelle dynamic; DIFFERENTIATION-RELATED PROTEIN; HUMAN APOLIPOPROTEIN-E; VIRUS CORE PROTEIN; ENDOPLASMIC-RETICULUM; DIACYLGLYCEROL ACYLTRANSFERASE; ACYL-COA; SACCHAROMYCES-CEREVISIAE; ALPHA-SYNUCLEIN; BINDING DOMAIN; PERILIPIN-A;

D O I：

10.1016/j.bbalip.2008.10.009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lipid droplets are the least characterized of cellular organelles. Long considered simple lipid storage depots, these dynamic and remarkable organelles have recently been implicated in many biological processes, and we are only now beginning to gain insights into their fascinating lives in cells. Here we examine what we know of the life of lipid droplets. We review emerging data concerning their cellular biology and present our thoughts on some of the most salient questions for investigation. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：459 / 466

页数：8

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