The Arabidopsis thaliana chloroplast inner envelope protein ARTEMIS is a functional member of the Alb3/Oxa1/YidC family of proteins

被引：21

作者：

Funes, S

Gerdes, L

Inaba, M

Soll, E

Herrmann, JM

机构：

[1] Univ Munich, Inst Physiol Chem, D-81377 Munich, Germany

[2] Univ Munich, Inst Bot, D-80638 Munich, Germany

来源：

FEBS LETTERS | 2004年 / 569卷 / 1-3期

关键词：

ARTEMIS; chloroplast; membrane insertion; mitochondria; oxal; Arabidopsis thaliana;

D O I：

10.1016/j.febslet.2004.05.055

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Arabidopsis thaliana protein ARTEMIS is an integral component of the chloroplast inner envelope required for chloroplast division. It contains a domain of significant homology to members of the Alb3/Oxa1/YidC protein family. Here, we show that upon expression in yeast mitochondria, ARTEMIS can partially take over the function of yeast Oxa1 in the insertion and assembly of mitochondrial membrane proteins. This identifies ARTEMIS as a functional member of the Alb3/Oxa1/YidC protein family and suggests the existence of a novel protein sorting pathway in chloroplasts which integrates polypeptides from the stroma into the inner envelope by an evolutionary conserved process. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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页码：89 / 93

页数：5

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