Surface adhesins of Staphylococcus aureus

被引：203

作者：

Clarke, Simon R. ^{[1
]}

Foster, Simon J. ^{[1
]}

机构：

[1] Univ Sheffield, Dept Mol Biol & Biotechnol, Sheffield S10 2TN, S Yorkshire, England

来源：

ADVANCES IN MICROBIAL PHYSIOLOGY, VOL 51 | 2006年 / 51卷

关键词：

D O I：

10.1016/S0065-2911(06)51004-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An important facet in the interaction between Staphylococcus aureus and its host is the ability of the bacterium to adhere to human extracellular matrix components and serum proteins. In order to colonise the host and disseminate, it uses a wide range of strategies, the molecular and genetic basis of which are multifactorial, with extensive functional overlap between adhesins. Here, we describe the current knowledge of the molecular features of the adhesive components of S. aureus, mechanisms of adhesion and the impact that these have on host-pathogen interaction.

引用

页码：187 / 225

页数：39

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