Bioresorbable stents: Current and upcoming bioresorbable technologies

被引：112

作者：

Ang, Hui Ying ^{[1
]}

Bulluck, Heerajnarain ^{[1
]}

Wong, Philip ^{[1
]}

Venkatraman, Subbu S. ^{[2
]}

Huang, Yingying ^{[2
]}

Foin, Nicolas ^{[1
,3
]}

机构：

[1] Natl Heart Ctr Singapore, 5 Hosp Dr, Singapore 169609, Singapore

[2] Nanyang Technol Univ, Sch Mat Sci & Engn, Nanyang Ave, Singapore 639798, Singapore

[3] DUKE NUS Med Sch, 8 Coll Rd, Singapore 169857, Singapore

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2017年 / 228卷

关键词：

Bioresorbable stents; Coronary artery disease; Coronary stent; CORONARY-ARTERY-DISEASE; OPTICAL COHERENCE TOMOGRAPHY; DRUG-ELUTING STENTS; VASCULAR SCAFFOLDS; PERCUTANEOUS CORONARY; MECHANICAL-PROPERTIES; METALLIC STENTS; 1-YEAR OUTCOMES; EVEROLIMUS; POLYMERS;

D O I：

10.1016/j.ijcard.2016.11.258

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Bioresorbable scaffolds ( BRS) represent a novel horizon in interventional cardiology for the treatment of coronary artery disease. The technology was introduced to overcome limitations of current metallic drug-eluting stents such as late in-stent restenosis and permanently caging the vessel. The concept of the BRS is to provide temporal support to the vessel during healing before being degraded and resorbed by the body, promoting restoration of the vessel vasomotion. Currently, there are several BRS that are under development or already commercially available. Although several reviews have elegantly covered progress of current clinical programs and newer scaffold technologies, little is available currently to describe the mechanistic differences between biomaterials used in current and newer bioresorbable technologies. This aim of this reviewis to discuss the status of the different BRS technologies and materials currently under investigation, explore the newer strategies being adopted to improve material mechanical properties and optimize BRS degradation and summarize the performance of BRS in the clinical setting so far. (C) 2016 Published by Elsevier Ireland Ltd.

引用

页码：931 / 939

页数：9

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