Intrahepatic cholangiocarcinoma

被引:106
作者
Chu, KM [1 ]
Lai, ECS [1 ]
AlHadeedi, S [1 ]
Arcilla, CE [1 ]
Lo, CM [1 ]
Liu, CL [1 ]
Fan, ST [1 ]
Wong, J [1 ]
机构
[1] UNIV PHILIPPINES, PHILIPPINES GEN HOSP, MANILA, PHILIPPINES
关键词
D O I
10.1007/s002689900233
中图分类号
R61 [外科手术学];
学科分类号
摘要
Intrahepatic cholangiocarcinoma is an uncommon neoplasm of liver compared with hepatocellular carcinoma. Hepatic resection seems to provide the only chance for therapeutic success. The records of 77 patients with intrahepatic cholangiocarcinoma treated over a 28-year period were studied to determine demographics, clinical features, laboratory findings, diagnostic tests, operative management, and results of therapy. Survival was analyzed according to three treatment group: conservative management, palliative operation, and hepatic resection. Conservative management was used for 15 patients, and hepatic resections were performed in 39 patients. The remaining 23 patients had laparotomy alone (10 patients), bile duct intubation (4 patients), hepatic artery ligation (3 patients), bilienteric bypass (3 patients), gastrojejunostomy (1 patient), insertion of a hepatic artery port for regional chemotherapy (1 patient), or open drainage of an abscess (1 patient). The median survival after conservative management, palliative operation, and hepatic resection were 1.8, 2.9, and, 12.2 months, respectively. After hepatic resection, patients without lymphatic permeation (p < 0.02) or hilar nodal metastases (p < 0.0003) survived significantly longer. We concluded that hepatic resection is indicated for intrahepatic cholangiocarcinoma when it is deemed resectable.
引用
收藏
页码:301 / 306
页数:6
相关论文
共 41 条
  • [31] RITCHIE JK, 1974, Q J MED, V43, P263
  • [32] INTRAHEPATIC CHOLANGIOCARCINOMA - RADIOLOGIC-PATHOLOGIC CORRELATION
    ROS, PR
    BUCK, JL
    GOODMAN, ZD
    ROS, AMV
    OLMSTED, WW
    [J]. RADIOLOGY, 1988, 167 (03) : 689 - 693
  • [33] Sanes S, 1942, AM J PATHOL, V18, P675
  • [34] Schlinkert R T, 1992, HPB Surg, V5, P95
  • [35] SCHRUMPF E, 1989, J HEPATOL, V9, P83, DOI DOI 10.1016/0168-8278(89)90342-5
  • [36] INTRAHEPATIC CHOLANGIOCARCINOMA IN HEPATOLITHIASIS - A FREQUENTLY OVERLOOKED DISEASE
    SHEENCHEN, SM
    CHOU, FF
    ENG, HL
    [J]. JOURNAL OF SURGICAL ONCOLOGY, 1991, 47 (02) : 131 - 135
  • [37] SINAWAT P, 1991, Journal of the Medical Association of Thailand, V74, P448
  • [38] TOBE T, 1987, CANCER-AM CANCER SOC, V60, P1400
  • [39] HEPATOBILIARY CARCINOMA ASSOCIATED WITH PRIMARY SCLEROSING CHOLANGITIS AND CHRONIC ULCERATIVE-COLITIS
    WEE, A
    LUDWIG, J
    COFFEY, RJ
    LARUSSO, NF
    WIESNER, RH
    [J]. HUMAN PATHOLOGY, 1985, 16 (07) : 719 - 726
  • [40] YAMAMOTO J, 1992, SURGERY, V111, P617