Simultaneous expression of different variant-specific surface proteins in single Giardia lamblia trophozoites during encystation

被引：21

作者：

Carranza, PG ^{[1
]}

Feltes, G ^{[1
]}

Ropolo, A ^{[1
]}

Quintana, SMC ^{[1
]}

Touz, MC ^{[1
]}

Luján, HD ^{[1
]}

机构：

[1] Univ Nacl Cordoba, Fac Ciencias Med, Catedra Bioquim & Biol Mol, RA-5000 Cordoba, Argentina

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 09期

关键词：

D O I：

10.1128/IAI.70.9.5265-5268.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A novel variant-specific surface protein (VSP) from Giardia was identified using the monoclonal antibody 9B10, raised against purified cyst walls. VSP9B10B is preferentially induced during encystation and expressed simultaneously with other VSPs on the surface of encysting trophozoites. These results support the hypothesis that encystation and antigenic variation are processes that are mechanistically related.

引用

页码：5265 / 5268

页数：4

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