BNAs: novel nucleic acid analogs with a bridged sugar moiety

被引：89

作者：

Imanishi, T ^{[1
]}

Obika, S ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Pharmaceut Sci, Osaka 5650871, Japan

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 16期

关键词：

D O I：

10.1039/b201557a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This article deals with our recent studies on the synthesis of BNAs (Bridged Nucleic Acids), novel nucleic acid analogs bearing a preorganized sugar conformation by a bridged structure. Duplex- and triplex-forming abilities of the BNA modified oligonucleotides are also described.

引用

页码：1653 / 1659

页数：7

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