Expression of a linker histone-like gene in the primordial germ cells in zebrafish

被引：33

作者：

Müller, K

Thisse, C

Thisse, B

Raz, E

机构：

[1] Max Planck Inst Biophys Chem, Germ Cell Dev, D-37077 Gottingen, Germany

[2] ULP, INSERM, CNRS, Inst Genet & Biol Mol & Cellulaire, F-67404 Illkirch Graffenstaden, France

来源：

MECHANISMS OF DEVELOPMENT | 2002年 / 117卷 / 1-2期

关键词：

zebrafish; linker histone; H1M; primordial germ cell;

D O I：

10.1016/S0925-4773(02)00174-0

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Similar to many other organisms, specification of primordial germ cells (PGCs) in zebraftsh occurs during early development and depends on inheritance of 'germ plasm' determinants. Following their specification, the PGCs exhibit characteristic transcriptional profile and cell behaviour. Here we describe the cloning, expression pattern and sub-cellular localization of the zebrafish H I type linker histone, HIM, which is specifically expressed in the PGCs in the second phase of their development. HIM transcripts are uniformly distributed during blastula stages, but become restricted to the PGCs during gastrulation and remain visible in PGCs as they migrate towards the region of the gonad. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：253 / 257

页数：5

共 16 条

[1] Germ plasm and molecular determinants of germ cell fate [J].