Histone acetylation: Chromatin in action

被引：398

作者：

Wade, PA

Pruss, D

Wolffe, AP

机构：

[1] Laboratory of Molecular Emoryology, National Institute of Child Health and Human Development, NIH, Bethesda

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1997年 / 22卷 / 04期

关键词：

D O I：

10.1016/S0968-0004(97)01016-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Histone acetylation acts as a landmark and determinant for chromatin function. Active roles in the transcription and assembly of chromatin have been discovered for histone acetyltransferases and deacetylases. This review highlights these roles and discusses their significance for the maintenance of cell differentiation.

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页码：128 / 132

页数：5

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