Histone acetylation: Chromatin in action

被引：398

作者：

Wade, PA

Pruss, D

Wolffe, AP

机构：

[1] Laboratory of Molecular Emoryology, National Institute of Child Health and Human Development, NIH, Bethesda

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1997年 / 22卷 / 04期

关键词：

D O I：

10.1016/S0968-0004(97)01016-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Histone acetylation acts as a landmark and determinant for chromatin function. Active roles in the transcription and assembly of chromatin have been discovered for histone acetyltransferases and deacetylases. This review highlights these roles and discusses their significance for the maintenance of cell differentiation.

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收藏

页码：128 / 132

页数：5

相关论文

共 30 条

[11] Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines [J].

Kuo, MH ;

Brownell, JE ;

Sobel, RE ;

Ranalli, TA ;

Cook, RG ;

Edmondson, DG ;

Roth, SY ;

Allis, CD .

NATURE, 1996, 383 (6597) :269-272

[12] Histone H4 acetylated at lysine 16 and proteins of the Drosophila dosage compensation pathway co-localize on the male X chromosome through mitosis [J].

Lavender, J. S. ;

Birley, A. J. ;

Palmer, M. J. ;

Kuroda, M. I. ;

Turner, B. M. .

CHROMOSOME RESEARCH, 1994, 2 (05) :398-404

[13] A POSITIVE ROLE FOR HISTONE ACETYLATION IN TRANSCRIPTION FACTOR ACCESS TO NUCLEOSOMAL DNA [J].

LEE, DY ;

HAYES, JJ ;

PRUSS, D ;

WOLFFE, AP .

CELL, 1993, 72 (01) :73-84

[14] HISTONE H4 AND THE MAINTENANCE OF GENOME INTEGRITY [J].

MEGEE, PC ;

MORGAN, BA ;

SMITH, MM .

GENES & DEVELOPMENT, 1995, 9 (14) :1716-1727

[15] The TAF(II)250 subunit of TFIID has histone acetyltransferase activity [J].

Mizzen, CA ;

Yang, XJ ;

Kokubo, T ;

Brownell, JE ;

Bannister, AJ ;

OwenHughes, T ;

Workman, J ;

Wang, L ;

Berger, SL ;

Kouzarides, T ;

Nakatani, Y ;

Allis, CD .

CELL, 1996, 87 (07) :1261-1270

[16] CHANGE IN THE PATTERN OF HISTONE BINDING TO DNA UPON TRANSCRIPTIONAL ACTIVATION [J].

NACHEVA, GA ;

GUSCHIN, DY ;

PREOBRAZHENSKAYA, OV ;

KARPOV, VL ;

EBRALIDSE, KK ;

MIRZABEKOV, AD .

CELL, 1989, 58 (01) :27-36

[17] HISTONE ACETYLATION REDUCES NUCLEOSOME CORE PARTICLE LINKING NUMBER CHANGE [J].

NORTON, VG ;

IMAI, BS ;

YAU, P ;

BRADBURY, EM .

CELL, 1989, 57 (03) :449-457

[18] The transcriptional coactivators p300 and CBP are histone acetyltransferases [J].

Ogryzko, VV ;

Schiltz, RL ;

Russanova, V ;

Howard, BH ;

Nakatani, Y .

CELL, 1996, 87 (05) :953-959

[19] The major cytoplasmic histone acetyltransferase in yeast: Links to chromatin replication and histone metabolism [J].

Parthun, MR ;

Widom, J ;

Gottschling, DE .

CELL, 1996, 87 (01) :85-94

[20] PARENTAL NUCLEOSOMES SEGREGATED TO NEWLY REPLICATED CHROMATIN ARE UNDERACETYLATED RELATIVE TO THOSE ASSEMBLED DE-NOVO [J].

PERRY, CA ;

ALLIS, CD ;

ANNUNZIATO, AT .

BIOCHEMISTRY, 1993, 32 (49) :13615-13623