Synthesis of non-proteinogenic amino acids from N-(4-toluenesulfonyl)dehydroamino acid derivatives

被引：14

作者：

Ferreira, PMT ^{[1
]}

Maia, HLS ^{[1
]}

Monteiro, LS ^{[1
]}

机构：

[1] Univ Minho, Dept Chem, P-4700320 Braga, Portugal

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 25期

关键词：

dehydroalanine; alpha-alcoxy-alpha-amino acids; alpha; alpha-diamino acids; beta-substituted dehydroamino acids;

D O I：

10.1016/S0040-4039(02)00811-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

By treating N-(4-toluenesulfonyl)-N-(tert-butyloxycarbonyl)-dehydroamino acid derivatives with different reactants under different conditions, a variety of new amino acids are obtained, viz. (i) alpha-alcoxy-alpha-amino acids, (ii) alpha,alpha-diamino acids and (iii) novel beta-substituted dehydroamino acids. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：4495 / 4497

页数：3

共 3 条

[1]

Michael addition of thiols, carbon nucleophiles and amines to F17 dehydroamino acid and dehydropeptide derivatives [J].