The role of mitochondria in the establishment of oocyte functional competence

被引：62

作者：

Cummins, JM ^{[1
]}

机构：

[1] Murdoch Univ, Div Vet & Biomed Sci, Perth, WA 6849, Australia

来源：

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2004年 / 115卷

关键词：

mitochondria; cytoplasm; oxidative phosphorylation; oocyte; ovulation; embryogenesis;

D O I：

10.1016/j.ejogrb.2004.01.011

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Mitochondria are maternally inherited, semi-autonomous organelles with their own genomes (mtDNA), largely responsible for the generation of energy in the form of cellular ATP. However, mitochondrial replication and transcription of mtDNA do not commence until well into embryonic differentiation. This means that the oocyte needs to contain sufficient stocks of functioning mitochondria to fuel the first few days of embryonic development. In this review, I examine how qualitative and quantitative aspects of mitochondria help us define the notion of functional competence. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

引用

页码：S23 / S29

页数：7

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