Efficient synthesis of thioglycosides via a Mitsunobu condensation

被引：30

作者：

Falconer, RA

Jablonkai, I

Toth, I ^{[1
]}

机构：

[1] Univ Queensland, Sch Pharm, Brisbane, Qld 4072, Australia

[2] Univ London, Sch Pharm, Dept Pharmaceut & Biol Chem, London WC1N 1AX, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 49期

关键词：

Mitsunobu reactions; thiosugars; glycosylation; glycolipids;

D O I：

10.1016/S0040-4039(99)01834-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thioglycosides were synthesised from 1-thiosugars and a series of alcohols under Mitsunobu conditions using 1,1'-(azodicarbonyl)dipiperidine and trimethylphosphine. The conditions were found to be compatible with a wide range of functionalities and protecting groups. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：8663 / 8666

页数：4

共 12 条

[1] A NOVEL LYSINE-PROTECTING PROCEDURE FOR CONTINUOUS-FLOW SOLID-PHASE SYNTHESIS OF BRANCHED PEPTIDES [J].