Osteoarthritis year in review 2016: biology

被引：71

作者：

Davidson, E. N. Blaney ^{[1
]}

van Caam, A. P. M. ^{[1
]}

van der Kraan, P. M. ^{[1
]}

机构：

[1] Radboudumc, Expt Rheumatol, Geert Grootepl 26-28, NL-6500 HB Nijmegen, Netherlands

来源：

OSTEOARTHRITIS AND CARTILAGE | 2017年 / 25卷 / 02期

关键词：

Osteoarthritis; Cartilage; Inflammation; Subchondral bone; NERVE GROWTH-FACTOR; ARTICULAR-CARTILAGE; ENVIRONMENTAL DISRUPTION; CELLULAR SENESCENCE; SUBCHONDRAL BONE; RAT MODEL; PAIN; AUTOPHAGY; DAMAGE; MICE;

D O I：

10.1016/j.joca.2016.09.024

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

This review highlights a selection of literature in the area of osteoarthritis biology published between the 2015 and 2016 Osteoarthritis Research Society International (OARSI) World Congress. Highlights were selected from a pubmed search covering cartilage, bone, inflammation and pain. A personal selection was made based, amongst other things, on topics presented during the 2015 conference. This covers circadian rhythm, TGF-beta signaling, autophagy, SIRT6, exercise, lubricin, TLR's, pain and NGF. Furthermore, in this review we have made an effort to connect these seemingly distant topics into one scheme of connections between them, revealing a theoretical big picture underneath. (C) 2016 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

引用

页码：175 / 180

页数：6

共 32 条

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Koga, Daisuke ;

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Morita, Sadao ;

Asou, Yoshinori .

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[2]

The interaction of lubricin/proteoglycan 4 (PRG4) with toll-like receptors 2 and 4: an anti-inflammatory role of PRG4 in synovial fluid [J].

Alquraini, Ali ;

Garguilo, Steven ;

D'Souza, Gerard ;

Zhang, Ling X. ;

Schmidt, Tannin A. ;

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Elsaid, Khaled A. .

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[3]

Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis [J].

Bouderlique, Thibault ;

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Newton, Phillip T. ;

Li, Lei ;

Barenius, Bjoern ;

Chagin, Andrei S. .

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The Relationship of Autophagy Defects to Cartilage Damage During Joint Aging in a Mouse Model [J].

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Olmer, Merissa ;

Kiosses, William B. ;

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[5]

Treatment with recombinant lubricin attenuates osteoarthritis by positive feedback loop between articular cartilage and subchondral bone in ovariectomized rats [J].

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Yu, Bin .

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van Beuningen, Henk M. ;

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[7]

Nociceptive Sensitizers Are Regulated in Damaged Joint Tissues, Including Articular Cartilage, When Osteoarthritic Mice Display Pain Behavior [J].

Driscoll, Clare ;

Chanalaris, Anastasios ;

Knights, Chancie ;

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The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity [J].

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Li, Xin ;

Jin, Ding ;

Wang, Ping ;

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Bellantuono, Ilaria ;

Fukada, Yoshitaka ;

Boot-Handford, Ray P. ;

Meng, Qing-Jun .

JOURNAL OF CLINICAL INVESTIGATION, 2016, 126 (01) :365-376

[9]

MiR-193b regulates early chondrogenesis by inhibiting the TGF-beta2 signaling pathway [J].

Hou, Changhe ;

Yang, Zibo ;

Kang, Yan ;

Zhang, Ziji ;

Fu, Ming ;

He, Aishan ;

Zhang, Zhiqi ;

Liao, Weiming .

FEBS LETTERS, 2015, 589 (09) :1040-1047

[10]

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Huang, Henry ;

Veien, Eric S. ;

Zhang, Hong ;

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Song, Jie .

PLOS ONE, 2016, 11 (01)

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