Synthesis of fluorescein derivatives containing metal-coordinating heterocycles

被引:11
作者
Clark, MA [1 ]
Hilderbrand, SA [1 ]
Lippard, SJ [1 ]
机构
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/j.tetlet.2004.07.131
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Fluorescein derivatives that contain Lewis basic heterocycles have been synthesized by concise reaction sequences. The preparation of these compounds proceeds by functionalization of an electron-rich aromatic precursor and subsequent condensation 14 to form the fluorophore. These compounds are envisioned as components of metal-based sensors. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7129 / 7131
页数:3
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