Facile synthesis of α-amino phosphonates in water using a Lewis acid-surfactant-combined catalyst

被引：221

作者：

Manabe, K ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] Univ Tokyo, CREST, Japan Sci & Technol Corp, Grad Sch Pharmaceut Sci,Bunkyo Ku, Tokyo 1130033, Japan

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 08期

关键词：

D O I：

10.1039/b000319k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three-component reactions of aldehydes, amines and triethyl phosphite were efficiently catalyzed by scandium tris(dodecyl sulfate) at ambient temperature in water to give various alpha-amino phosphonates in high yields.

引用

页码：669 / 670

页数：2

共 19 条

[1] AFARINKIA K, 1990, SYNLETT, P415
[2] URYLENEDIPHOSPHONATES - GENERAL METHOD FOR SYNTHESIS OF ALPHA-UREIDOPHOSPHONATES AND RELATED STRUCTURES
BIRUM, GH
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (02) : 209 - 213
[3] THE SYNTHESIS OF ESTERS OF SUBSTITUTED AMINO PHOSPHONIC ACIDS
FIELDS, EK
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1952, 74 (06) : 1528 - 1531
[4] Synthesis of natural products containing a C-P bond
Fields, SC
[J]. TETRAHEDRON, 1999, 55 (42) : 12237 - 12272
[5] Grieco P.A., 1998, Organic synthesis in water
[6] HEANEY F, 1995, COMPREHENSIVE ORGANI, V4, P10
[7] HUBER IJW, 1977, SYNTHESIS-STUTTGART, P883
[8] Scandium trisdodecylsulfate (STDS). A new type of Lewis acid that forms stable dispersion systems with organic substrates in water and accelerates aldol reactions much faster in water than in organic solvents
Kobayashi, S
Wakabayashi, T
[J]. TETRAHEDRON LETTERS, 1998, 39 (30) : 5389 - 5392
[9] LASCHAT S, 1992, SYNTHESIS-STUTTGART, P90
[10] Remarkable enhancement of reactivity by Bronsted acids in aldol reactions mediated by Lewis acid-surfactant-combined catalysts in water
Manabe, K
Kobayashi, S
[J]. TETRAHEDRON LETTERS, 1999, 40 (19) : 3773 - 3776

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