Treatment of methanol poisoning with intravenous 4-methylpyrazole

被引：57

作者：

Burns, MJ ^{[1
]}

Graudins, A ^{[1
]}

Aaron, CK ^{[1
]}

McMartin, K ^{[1
]}

Brent, J ^{[1
]}

机构：

[1] UNIV MASSACHUSETTS, MED CTR, DEPT EMERGENCY MED, DIV TOXICOL, WORCESTER, MA USA

来源：

ANNALS OF EMERGENCY MEDICINE | 1997年 / 30卷 / 06期

关键词：

D O I：

10.1016/S0196-0644(97)70060-X

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Treatment of human methanol poisoning with the alcohol dehydrogenase inhibitor, 4-methylpyrazole (fomepizole), has not been previously described. We report the clinical and toxicokinetic data of a patient with methanol poisoning who was treated with fomepizole. Formic acid levels remained undetectable during fomepizole treatment, the toxic effects of methanol were prevented, and the patient made a full recovery.

引用

页码：829 / 832

页数：4

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