Speed versus accuracy in a fast convolution photon dose calculation for conformal radiotherapy

被引:25
作者
Bedford, JL
机构
[1] Inst Canc Res, Joint Dept Phys, Sutton SM2 5PT, Surrey, England
[2] Royal Marsden NHS Trust, Sutton SM2 5PT, Surrey, England
关键词
D O I
10.1088/0031-9155/47/19/303
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A convolution dose calculation for megavoltage photon beams is described and the compromise between speed and accuracy examined. The algorithm is suitable for treatment planning optimization, where the need is for a fast, flexible method requiring minimal beam data but providing an accurate result. The algorithm uses a simple tabular beam model, together with a discrete scatter kernel. These beam parameters are fitted either to a measured dose distribution, or to a dose distribution calculated using a more accurate dose calculation algorithm. The calculation is then applied to pelvic and thoracic conformal plans, and the results compared with those provided by a commercial radiotherapy treatment planning system (Pinnacle(3), Philips Radiation Oncology Systems, Milpitas, CA), which has been verified against measurements. The calculation takes around 4 s to compute a 100 x 100 rum field, and agreement of the dose-volume histograms with the commercial treatment planning system is to within 5% dose or 8% volume. Use of a grid resolution coarser than 5 x 5 x 5 rum is found to be inaccurate, whereas calculating primary dose on a coarse grid and interpolating is found to increase speed without significantly reducing accuracy. Kernel resolution influences the speed and accuracy, but using 12 discrete points provides a fast result with a limited error. Thus, the algorithm is suitable for optimization applications.
引用
收藏
页码:3475 / 3484
页数:10
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