IPSCs, a Promising Tool to Restore Muscle Atrophy

被引：5

作者：

Pareja-Galeano, Helios ^{[1
,2
]}

Sanchis-Gomar, Fabian ^{[2
]}

Emanuele, Enzo ^{[3
]}

Esther Gallardo, Maria ^{[2
,4
,5
]}

Lucia, Alejandro ^{[1
,2
]}

机构：

[1] European Univ Madrid, Madrid 28670, Spain

[2] Hosp 12 Octubre I 12, Res Inst, Madrid, Spain

[3] 2E Sci, Robbio, PV, Italy

[4] UAM CSIC, Fac Med, Dept Bioquim, Inst Invest Biomed Alberto Sols, Madrid, Spain

[5] Ctr Invest Biomed Red Enfermedades Raras CIBERER, Madrid, Spain

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 2016年 / 231卷 / 02期

关键词：

PLURIPOTENT STEM-CELLS; SARCOPENIA;

D O I：

10.1002/jcp.25114

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Induced pluripotent stem cells (iPSCs) are a promising tool for regenerative medicine in chronic conditions associated with muscle atrophy since iPSCs are easier to obtain, pose less ethical limitations and can better capture human genetic diversity compared with human embryonic stem cells. We highlight the potentiality of iPSCs for treating muscle-affecting conditions for which no effective cure is yet available, notably aging sarcopenia and inherited neurometabolic conditions. J. Cell. Physiol. 231: 259-260, 2016. (c) 2015 Wiley Periodicals, Inc.

引用

页码：259 / 260

页数：2

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